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Cincinnati Children’s Hospital Medical Center Study Looks at CARD14 & Healthy Skin Barrier Formation

A novel signaling pathway could help treat atopic dermatitis and psoriasis, say authors.

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By: Christine Esposito

Editor-in-Chief

CARD14 directly binds and regulates MYC, a protein involved in controlling cell growth that can contribute to cancer when it malfunctions. A study shows that the proper interaction between these two proteins is important for a healthy skin barrier. (graphic: Cincinnati Children's)

Experts in human genetics and asthma research at Cincinnati Children’s Hospital Medical Center (Cincinnati Children’s) report discovering a novel molecular signaling pathway that plays a crucial role in maintaining the skin barrier. The findings could lead to new ways to prevent atopic dermatitis and psoriasis, say the scientists behind the research. The study was published online in Cell Reports on Aug. 6, 2024. The title of the study is: “Regulation of MYC by CARD14 in human ep...

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